The Avance III HD architecture is based on a forward-thinking electronics concept that delivers an unprecedented level of digital control, fast NMR, high speed spectroscopy, flexibility and exceptionally pure NMR frequency generation. The AVANCE III HD spectrometer is designed around an advanced digital concept that provides an optimized pathway for highest speed RF generation and data acquisition with a highly modular and scalable transmitter and receiver channel architecture.

The AVANCE III HD features new digital RF synthesizer, further enhanced receiver electronics, redesigned preamplifiers, extended Digital Lock^TM and SmartVT^TM capabilities. The new RF synthesizer offers significantly increased digital integration, incorporating a lower phase noise local oscillator (LO) and a high speed DA converter running at 960 MHz. This enables extended digital RF power settings up to NMR frequencies of 1.2 GHz.

An AVANCE III HD spectrometer can be configured in three different ways:

As a NanoBay system equipped with an internal IPSO AQS Unit

As an OneBay or TwoBay system equipped with the extended IPSO 19" Unit.

The BSMS/2 with ELCB units contain a set of higher integrated boards (ELCB and SCB20) which have replaced the former controller, lock and shim boards (CPU/3, LCB, all variants of SCB7/13). These boards provide better performance, higher resolution and increased stability. The shim boards have been unified - a standard SCB20 now provides the necessary precision for many variants of connected shim systems.

General information common to most Probes can be found here. See the appropriate NMR probe documentation for details.

The HPPR/2 amplifies, filters and routes the NMR response signals from the probe to the RX22 receiver. It switches the RF transmitter output to the probe.

General handling and maintenance information for all magnets can be found here. Specific documents are supplied with each magnet.

DNP NMR allows the characterization, at the molecular level, of hybrid organic silica material. These materials are key compounds for applications in catalysis, drug delivery, separation and purification devices. The DNP Control System Console controls and supervises the unique high power microwave source and its infrastructure.

The new GREAT for AVANCE III no longer applies preemphasis to the gradients on its own. Instead, the preemphasis is digitally computed and applied to the digital gradient data by an external unit, the DPP (Digital Preemphasis Processor). The preemphasis is now calculated by a DSP and works on the digital input of the GREAT.

Bruker Automation allows the user to easily and effectively perform automatic experiments.